I like the colour scheme of the 2018 Defy Advance Pro 1 with the green trim over the single colour Addict 10. But I would spend the extra cash and buy the SCOTT Addict Gravel 10 Disc Bike - 2018....mmm nice.
This is a pretty close comparison, but I'd go with the Addict for four reasons:
Any good bike shop could deal with 2 & 3 by simply swapping out the wheels and tyres.
#2 agreed I wouldn't like a 16spoke front disc wheel either.
re #3 - Dave M have you tried road tubeless tyres? (I am not going back to tubes anytime soon)
Trevor - consider the Focus Paralane. It has got some clever features.